What is the most valuable card in 2021 Panini Classics Premium Edition Significant Signatures?

The most valuable card in 2021 Panini Classics Premium Edition Significant Signatures is the Ja'Marr Chase #157, worth around $1,000.00 ungraded — graded copies sell for more.

2021 Panini Classics Premium Edition Significant Signatures

Football · 167 cards · checklist & values

Part of 2021 Panini Classics Football →

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Cards tracked

167

With a value

Value range

$1–$1,000

Median value

$17

Ripbin tracks 52 priced cards from 2021 Panini Classics Premium Edition Significant Signatures, with values from $1 to $1,000 — the top 10 cards account for 76% of the set's tracked value.

Prices last updated Sep 2026

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2021 Panini Classics Premium Edition Significant Signatures checklist, prices and values — all 167 cards in one place, led by Ja'Marr Chase, Peyton Manning, Justin Herbert.

Every card below links to a full price page: grade-by-grade values, live eBay listings, and price history. Collectors use this checklist to value collections and find deals.

Most valuable 2021 Panini Classics Premium Edition Significant Signatures cards

Price distribution

Under $2530 (58%)

$25–$10014 (27%)

$100–$5007 (13%)

$500+1 (2%)

Card	Ungraded	PSA 9	PSA 10	BGS 10
Ja'Marr Chase#157	$1,000.00	—	—	—
Peyton Manning#114	$449.00	—	—	—
Justin Herbert#99	$349.31	—	—	—
Josh Jacobs#97	$200.00	—	—	—
Taysom Hill#14	$200.00	—	—	—
Justin Fields#154	$149.17	$129.99	$200.50	$261.00
Christian McCaffrey#17	$109.78	—	—	—
Sam Darnold#16	$100.00	—	—	—
Justin Jefferson#49	$93.18	$131.56	—	—
Travis Etienne Jr#164	$55.38	$40.00	—	—
Marcus Allen#109	$175.27	—	—	—
Jaylen Waddle#158	$80.02	$300.00	—	—
Amon-Ra St. Brown#178	$97.50	—	—	—
Warren Moon#132	$64.00	—	—	—
CeeDee Lamb#52	$55.59	—	—	—
Kyle Trask#159	$50.01	—	—	—
Eric Dickerson#137	$50.00	—	—	—
Donald Driver#131	$41.00	—	—	—
Darren Waller#95	$15.78	—	—	—
Shaun Alexander#149	$29.00	—	—	—
Patrick Surtain II#195	$59.99	$150.00	—	—
Cam Akers#80	$32.45	—	—	—
Tee Higgins#30	$21.29	—	$41.00	$53.00
Zach Wilson#152	$82.40	$96.75	—	—
Jonathan Taylor#7	$19.75	—	—	—
Mark Andrews#26	$41.08	—	—	—
Marques Colston#144	$14.95	—	—	—
Rhamondre Stevenson#187	$34.75	—	—	—
Zach Thomas#140	$214.60	—	—	—
Antonio Gibson#62	$32.46	—	—	—
Javonte Williams#165	$20.97	—	—	—
Nico Collins#180	$52.58	—	—	—
Chuba Hubbard#175	$25.99	—	—	—
Chris Godwin#23	$69.95	—	—	—
LaDainian Tomlinson#148	$9.80	—	—	—
Najee Harris#163	$37.05	—	—	—
Larry Johnson#135	$8.00	—	—	—
Pat Freiermuth#182	$7.49	—	—	—
Austin Ekeler#100	$7.31	—	—	—
Marcus Maye#74	$6.29	—	—	—
Josh Palmer#179	$3.76	—	—	—
Jacob Harris#188	$3.69	—	—	—
Ian Book#177	$3.13	—	—	—
Dyami Brown#173	$3.05	—	—	—
Michael Carter#185	$2.51	—	—	—
Anthony Schwartz#181	$2.25	—	—	—
Brandin Cooks#10	$2.25	—	—	—
Myles Gaskin#68	$2.14	—	—	—
Jaelon Darden#183	$1.75	—	—	—
Ihmir Smith-Marsette#192	$1.50	—	—	—
Kene Nwangwu#184	$1.04	—	—	—
Tylan Wallace#176	$0.99	—	—	—
Ray Lewis#101	—	—	—	—
Brian Urlacher#104	—	—	—	—
Charles Haley#105	—	—	—	—
Barry Sanders#107	—	—	—	—
Randy Moss#108	—	—	—	—
Tim Brown#110	—	—	—	—
Joe Montana#111	—	—	—	—
Bo Jackson#112	—	—	—	—

Showing the top 60 of 167 cards. View the full 2021 Panini Classics Premium Edition Significant Signatures checklist (167 cards) →

Frequently asked questions

What is the most valuable card in 2021 Panini Classics Premium Edition Significant Signatures?: The most valuable card in 2021 Panini Classics Premium Edition Significant Signatures is the Ja'Marr Chase #157, worth around $1,000.00 ungraded — graded copies sell for more.
How many cards are in 2021 Panini Classics Premium Edition Significant Signatures?: Ripbin tracks 167 2021 Panini Classics Premium Edition Significant Signatures cards, 52 of them with current values. Browse the full list above.
How much are 2021 Panini Classics Premium Edition Significant Signatures cards worth?: 2021 Panini Classics Premium Edition Significant Signatures cards range from $1 to $1,000, with a median value of $17. The top 10 cards hold about 76% of the set's tracked value.

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