The 10 Most Valuable 2021 Panini Classics Premium Edition Significant Signatures Football Cards
The most valuable 2021 Panini Classics Premium Edition Significant Signatures Football card is the 2021 Panini Classics Premium Edition Significant Signatures Ja'Marr Chase #157 at $1,000.00 as of September 28, 2026.
By Ripbin Research · Updated 2026-09-28 · prices from live market data
Shop 2021 Panini Classics Premium Edition Significant Signatures Football cards on eBay
Affiliate — we may earn a commissionThe 10 most valuable 2021 Panini Classics Premium Edition Significant Signatures Football cards in the Ripbin catalog carry a combined raw market value of $2,781.77, topped by a $1,000.00 card.
Just missed the cut
- #11 2021 Panini Classics Premium Edition Significant Signatures Marcus Allen #109$85.65
- #12 2021 Panini Classics Premium Edition Significant Signatures Jaylen Waddle #158$80.02
- #13 2021 Panini Classics Premium Edition Significant Signatures Amon-Ra St. Brown #178$69.00
- #14 2021 Panini Classics Premium Edition Significant Signatures Warren Moon #132$64.00
- #15 2021 Panini Classics Premium Edition Significant Signatures CeeDee Lamb #52$55.59
- #16 2021 Panini Classics Premium Edition Significant Signatures Kyle Trask #159$50.01
- #17 2021 Panini Classics Premium Edition Significant Signatures Eric Dickerson #137$50.00
- #18 2021 Panini Classics Premium Edition Significant Signatures Donald Driver #131$41.00
- #19 2021 Panini Classics Premium Edition Significant Signatures Darren Waller #95$35.00
- #20 2021 Panini Classics Premium Edition Significant Signatures Shaun Alexander #149$29.00
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