The 10 Most Valuable 2021 Panini Donruss Optic Signature Series Football Cards
The most valuable 2021 Panini Donruss Optic Signature Series Football card is the 2021 Panini Donruss Optic Signature Series Jalen Hurts #SS-JU at $139.99 as of October 20, 2026.
By Ripbin Research · Updated 2026-10-20 · prices from live market data
Shop 2021 Panini Donruss Optic Signature Series Football cards on eBay
Affiliate — we may earn a commissionThe 10 most valuable 2021 Panini Donruss Optic Signature Series Football cards in the Ripbin catalog carry a combined raw market value of $443.10, topped by a $139.99 card.
Just missed the cut
- #11 2021 Panini Donruss Optic Signature Series Younghoe Koo #SS-YK$11.11
- #12 2021 Panini Donruss Optic Signature Series Gilbert Brown #SS-GB$10.46
- #13 2021 Panini Donruss Optic Signature Series AJ Dillon #SS-AJ$9.61
- #14 2021 Panini Donruss Optic Signature Series Cole Kmet #SS-CK$8.59
- #15 2021 Panini Donruss Optic Signature Series Antwaan Randle El #SS-AR$6.96
- #16 2021 Panini Donruss Optic Signature Series Jack Youngblood #SS-JY$6.58
- #17 2021 Panini Donruss Optic Signature Series Marquez Valdes Scantling #SS-MV$5.04
- #18 2021 Panini Donruss Optic Signature Series Vance Johnson #SS-VJ$5.00
- #19 2021 Panini Donruss Optic Signature Series Darius Slayton #SS-DS$4.08
- #20 2021 Panini Donruss Optic Signature Series Linval Joseph #SS-LJ$2.93
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