The 10 Most Valuable 2022 Donruss Optic Signature Series Baseball Cards
The most valuable 2022 Donruss Optic Signature Series Baseball card is the 2022 Donruss Optic Signature Series Ronald Acuna Jr. #SIGS-RA at $42.06 as of October 3, 2026.
By Ripbin Research · Updated 2026-10-03 · prices from live market data
Shop 2022 Donruss Optic Signature Series Baseball cards on eBay
Affiliate — we may earn a commissionThe 10 most valuable 2022 Donruss Optic Signature Series Baseball cards in the Ripbin catalog carry a combined raw market value of $98.42, topped by a $42.06 card.
Just missed the cut
- #11 2022 Donruss Optic Signature Series Tylor Megill #SIGS-TM$2.80
- #12 2022 Donruss Optic Signature Series Jose Siri #SIGS-JS$2.79
- #13 2022 Donruss Optic Signature Series Aaron Ashby #SIGS-AA$2.78
- #14 2022 Donruss Optic Signature Series Chas McCormick #SIGS-CM$2.77
- #15 2022 Donruss Optic Signature Series Connor Wong #SIGS-CW$2.48
- #16 2022 Donruss Optic Signature Series Yency Almonte #SIGS-YA$2.38
- #17 2022 Donruss Optic Signature Series Juan Yepez #SIGS-JY$2.25
- #18 2022 Donruss Optic Signature Series Eli Morgan #SIGS-EM$2.11
- #19 2022 Donruss Optic Signature Series Jon Heasley #SIGS-JH$2.09
- #20 2022 Donruss Optic Signature Series Luis Urias #SIGS-LU$2.02
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