The 10 Most Valuable 2021 Topps Base Set Baseball Cards
The most valuable 2021 Topps Base Set Baseball card is the 2021 Topps Base Set Rickey Henderson SSP #613 at $91.00 as of October 19, 2026.
By Ripbin Research · Updated 2026-10-19 · prices from live market data
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Affiliate — we may earn a commissionThe 10 most valuable 2021 Topps Base Set Baseball cards in the Ripbin catalog carry a combined raw market value of $490.47, topped by a $91.00 card.
#12021 Topps Base Set Rickey Henderson SSP #613
$91.00PSA 10 ~$174.78#22021 Topps Base Set Francisco Lindor SSP #489
$64.99PSA 10 ~$175.00#42021 Topps Base Set Derek Jeter SSP #561
$47.29PSA 10 ~$105.25#52021 Topps Base Set Roberto Clemente SSP #412
$46.32PSA 10 ~$137.95#102021 Topps Base Set Willie Mays SSP #616
$33.76PSA 10 ~$85.43
Just missed the cut
- #11 2021 Topps Base Set Stan Musial SSP #566$32.84
- #12 2021 Topps Base Set Cal Ripken Jr. SSP #346$30.50
- #13 2021 Topps Base Set Roberto Clemente SP 5x7 Gold #130$29.99
- #14 2021 Topps Base Set Jackie Robinson SSP #347$28.22
- #15 2021 Topps Base Set Ken Griffey Jr. SSP #506$26.93
- #16 2021 Topps Base Set Willie Mays SP 5x7 Gold #227$26.45
- #17 2021 Topps Base Set Hank Aaron SP 5x7 Gold #120$19.99
- #18 2021 Topps Base Set Lou Gehrig SP 5x7 Gold #186$19.99
- #19 2021 Topps Base Set Tony Gwynn SP 5x7 Gold #266$19.99
- #20 2021 Topps Base Set Ken Griffey Jr. SP 5x7 Gold #247$17.49
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